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Wednesday, July 22, 2020 | History

6 edition of Cancer Therapy: Monoclonal Antibodies, Lymphokines found in the catalog.

Cancer Therapy: Monoclonal Antibodies, Lymphokines

New Developments in Surgical Oncology and Chemo-And Hormonal Therapy

by H. G. Beger

  • 344 Want to read
  • 39 Currently reading

Published by Springer .
Written in English


Edition Notes

ContributionsG. Schulz (Editor)
The Physical Object
Number of Pages308
ID Numbers
Open LibraryOL7444143M
ISBN 10038719293X
ISBN 109780387192932

Abstract. This book consists of three parts, each containing several papers. The part headings are: Techniques of Immunization and Hybrid Construction, Production and Modification of Antibodies and Lymphokines, and Applications of Monoclonal Lymphoid Products. Antibodies, Monoclonal Antibodies, Monoclonal, Humanized Endothelial Growth Factors Intercellular Signaling Peptides and Proteins Lymphokines Tumor .

A Beginner's Guide to Targeted Cancer Treatments provides an understanding of how cancer works and the many new treatments available. Using over original illustrations, this accessible handbook covers the biology and mechanisms behind a huge range of targeted drug treatments, including many new immunotherapies. Cancer immunotherapy (sometimes called immuno-oncology) is the artificial stimulation of the immune system to treat cancer, improving on the immune system's natural ability to fight the is an application of the fundamental research of cancer immunology and a growing subspeciality of oncology.. Cancer immunotherapy exploits the fact that cancer cells often have tumor antigens.

  Monoclonal antibody therapy involves making large quantities of antibodies that recognize antigens that tend to be found on the surfaces of cancer . With patients randomly assigned to treatment groups (40 to placebo, 37 to low-dose antibody, and 39 to high-dose antibody), there was a significant prolongation of the time to progression of disease in the high-dose--antibody group as compared with the placebo group (hazard ratio, ; P.


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Cancer Therapy: Monoclonal Antibodies, Lymphokines by H. G. Beger Download PDF EPUB FB2

Cancer Therapy Monoclonal Antibodies, Lymphokines New Developments in Surgical Oncology and Chemo- and Hormonal Therapy Editors: Beger, H.G., Büchler, M., Reisfeld, R.A., Schulz, G. (Eds.). Cancer therapy: monoclonal antibodies, lymphokines: new developments in surgical oncology and chemo- and hormonal therapyPages: Get this from a library.

Cancer therapy: monoclonal antibodies, lymphokines: new developments in surgical oncology and chemo- and hormonal therapy. [H G Beger;]. Get this from a library. Cancer Therapy: Monoclonal Cancer Therapy: Monoclonal Antibodies, Lymphokines New Developments in Surgical Oncology and Chemo- and Hormonal Therapy.

[H G Beger; Markus Büchler; Ralph A Reisfeld; G Schulz] -- A variety of new cancer therapy modalities are discussed and evaluated in this book. It aims to demonstrate that the combination of classical chemo- and radiotherapy with new approaches.

Abstract Biologicals and biological response modifiers (BRMs) represent a new class of agents for cancer therapy. Historically, there have been many attempts to stimulate the immune response with n Cited by:   Read here ?book= Read Cancer Therapy: Monoclonal Antibodies Lymphokines New Developments in Surgical Oncology.

Monoclonal Antibodies, Lymphokines New Developments in Surgical Oncology and Chemo- and Hormonal Therapy, Cancer Therapy, B. Greifenberg, K.H. Link, Springer. Des milliers de livres avec la livraison chez vous Lymphokines book 1 jour ou en magasin avec -5% de réduction.

This book emphasizes the unique property of a cancer cell and describes in detail how a novel therapeutic approach can be developed.

This compilation consists of 11 chapters. Chapters 1, 2, 5, 6, and 7 deal with emerging areas of cancer therapy, such as the use of interferon, monoclonal antibodies, liposomes, lymphokines, and immunomodulators. For example, some monoclonal antibodies mark cancer cells so that the immune system will better recognize and destroy them.

An example is rituximab, which binds to a protein called CD20 on B cells and some types of cancer cells, causing the immune system to kill them. B cells are a type of white blood cell. Other monoclonal antibodies bring T cells close to cancer cells, helping the immune cells kill the cancer cells.

Learn more about T-cell transfer therapy. Monoclonal antibodies, which are immune system proteins created in the lab that are designed to bind to specific targets on cancer cells. Some monoclonal antibodies mark cancer cells so that they will be better seen and destroyed by the immune system.

Such monoclonal antibodies are a type of immunotherapy. A variety of new cancer therapy modalities are discussed and evaluated in this book. It aims to demonstrate that the combination of classical chemo- and radiotherapy with new approaches in the field of immunotherapy can result in an improved treatment modality.

Immunotherapy in this context consists of therapy with monoclonal antibodies, hematopoietic growth factors and other lymphokines. Monoclonal antibodies are laboratory-produced molecules engineered to serve as substitute antibodies that can restore, enhance or mimic the immune system's attack on cancer cells.

They are designed to bind to antigens that are generally more numerous on the surface of cancer cells than healthy cells. How do monoclonal antibody drugs work. Monoclonal antibodies are used to treat many diseases, including some types of cancer.

To make a monoclonal antibody, researchers first have to identify the right antigen to attack. Finding the right antigens for cancer cells is not always easy, and so far mAbs have proven to be more useful against some cancers than others.

Monoclonal antibodies have emerged as effective therapeutic agents for many human malignancies. However, the ability of antibodies to initiate tumor antigen-specific immune responses has not received as much attention as other mechanisms of antibody action. Introduction. The development of monoclonal antibodies (mAbs), which act via antibody-dependent cell-mediated cytotoxicity (ADCC), represented a significant advance in cancer immunotherapy.

1 Bispecific antibodies (bsAbs), which bind to tumor cells and T-cells, and act via T-cell-mediated lysis, are currently in clinical development. 2, 3 The trifunctional antibody (trAb).

Vaccines for Cancer Immunotherapy provides a reference for cancer treatment for clinicians and presents a well-organized resource for determining high-potential research areas.

The book considers that this promising modality can be made more feasible as a treatment for cancer. Hafeez U, Gan HK, Scott AM. Monoclonal antibodies as immunomodulatory therapy against cancer and autoimmune diseases. Curr Opin Pharmacol. ; Hill JA, Giralt S, Torgerson TR, et al.

CAR-T- and a side order of IgG, to go?- Immunoglobulin replacement in patients receiving CAR-T cell therapy. Blood Rev. [Accepted manuscript. Read "Cancer Therapy Monoclonal Antibodies, Lymphokines New Developments in Surgical Oncology and Chemo- and Hormonal Therapy" by B.

Greifenberg available from Rakuten Kobo. A variety of new cancer therapy modalities are discussed and evaluated in this book.

It aims to demonstrate that the com Brand: Springer Berlin Heidelberg. Keywords:Cancer therapies, chemotherapy, immunotoxins, monoclonal antibodies, small molecule inhibitors.

Abstract:Cancer is one of the leading causes of death in the United States along with heart disease. The hallmark of cancer treatment has been conventional chemotherapy.

This is a list of therapeutic, diagnostic and preventive monoclonal antibodies, antibodies that are clones of a single parent used as drugs, the International Nonproprietary Names (INNs) end in -mab. The remaining syllables of the INNs, as well as the column Source, are explained in Nomenclature of monoclonal antibodies.

About this book. Introduction. The rapid and continuous upsurge of interesting data in the subject of tumor immunology necessitates the publication of an annual series to furnish the updated materials to the students, researchers, and clinicians in this rapidly advancing field.

Oncogene, interferon, lymphokines, monoclonal antibodies.Lymphokines, monoclonal antibodies, and other biological response modifiers in the treatment of cancer Robert K.

Oldham, Gary B. Thurman, James E. Talmadge, Henry C. Stevenson, Kenneth A. Foon Pathology & Microbiology.Each type targets something in or around the cancer cell that is helping it grow and survive.

You can read more about the most common types below. A targeted therapy can belong to more than one of these groups. For example, a monoclonal antibody may also block cancer cell growth. So it may also be called a cancer growth inhibitor.